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Previous highlights

2024 Paper Highlights

May 2024

  • Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study (link)

  • Early switch to oral antibiotic therapy in patients with low-risk neutropenic sepsis (EASI-SWITCH): a randomized non-inferiority trial (link)

April 2024

  • Impact of doxycycline on Clostridioides difficile infection in patients hospitalized with community-acquired pneumonia (link)

  • Inappropriate Diagnosis of Pneumonia Among Hospitalized Adults (link)

  • Five-Year Outcomes of the Partial Oral Treatment of Endocarditis (POET) Trial (link)


March 2024

  • Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomized trial (link)

Before 2024

  • Impact of Enterococcus faecalis Endocarditis Treatment on Risk of Relapse (link)

  • Treatment With Reduced-Dose Trimethoprim-Sulfamethoxazole Is Effective in Mild to Moderate Pneumocystis jirovecii Pneumonia in Patients With Hematologic Malignancies (link)

  • Creation and Internal Validation of a Clinical Predictive Model for Fluconazole Resistance in Patients With Candida Bloodstream Infection (link)

  • Oral Versus Standard Antimicrobial Treatment for Pyogenic Native Vertebral Osteomyelitis: A Single-Center, Retrospective, Propensity Score-Balanced Analysis (link)

  • Persistent MRSA Bacteremia: Resetting the Clock for Optimal Management (link)

  • Duration of Treatment for Pseudomonas aeruginosa bloodstream infection (BSI). A Retrospective Study (link)

  • Antibiotic Overuse and Stewardship at Hospital Discharge: The Reducing Overuse of Antibiotics at Discharge Home Framework (link)

  • Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis (link)

  • Three Weeks Versus Six Weeks of Antibiotic Therapy for Diabetic Foot Osteomyelitis: A Prospective, Randomized, Noninferiority Pilot Trial (link)

  • Antimicrobial stewardship in high-risk febrile neutropenic patients (link)

  • The Incidence of Ocular Complications in Candidemic Patients and Implications for the Practice of Routine 
Eye Exams (link)

  • Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection (link)

  • Sign of the Times: Updating Infective Endocarditis Diagnostic Criteria to Recognize Enterococcus faecalis as a Typical Endocarditis Bacterium (link)

  • Efficacy of Ceftazidime-avibactam Plus Aztreonam in Patients With Bloodstream Infections Caused by Metallo-β-lactamase–Producing Enterobacterales (link)

  • Short-course aminoglycosides as adjunctive empirical therapy in patients with Gram-negative bloodstream infection , a cohort study (link)

  • Comparative Effectiveness of Switching to Daptomycin  Versus Remaining on Vancomycin Among Patients With Methicillin-resistant Staphylococcus aureus Bloodstream Infections (link)

  • Rifampin combination therapy in Staphylococcal prosthetic joint infections: a randomized controlled trial (link)

  • Antibiotics versus no therapy in kidney transplant recipients with asymptomatic bacteriuria (ABU): a pragmatic, multicentre, randomised controlled trial (link)

  • Outcomes of OPAT with Ceftriaxone for MSSA Blood Stream Infection (BSI)- A Single Center Observational Study (link)

  • Switch from parenteral to oral antibiotics for brain abscesses: a retrospective cohort study of 109 patients (link)

  • Piperacillin-Tazobactam Added to Vancomycin Increases Risk for AKI: Fact or Fiction? (link)

  • Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study (link)

  • Association Between Penicillin Allergy Documentation and Antibiotic Use (link)

  • Efficacy of Early Oral Switch with β-Lactams for Low-Risk Staphylococcus aureus Bacteremia (link)

  • Effect of CRP guided Antibiotic Treatment Duration vs. 7-Day Rx, or 14-Day Rx in Uncomplicated Gram-Negative Bacteraemia (link)

  • Reappraisal of Linezolid Dosing in Renal Impairment to Improve Safety (link)

  • Antibiotic treatment for 6 days versus 12 days in patients with severe cellulitis: a multicentre randomised, double-blind, placebo-controlled, non-inferiority trial (link)

  • Pneumococcal Urinary Antigen Testing in United States Hospitals: A Missed Opportunity for Antimicrobial Stewardship (link)

  • Four versus six weeks of antibiotic therapy for osteoarticular infections after implant removal: a randomized trial (link)

  • Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients (link)

  • Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment (link)

  • When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit (link)

  • Efficacy of Ceftriaxone 1 g daily Versus 2 g daily for The Treatment of Community-Acquired Pneumonia: A Systematic Review with Meta-Analysis (link)

  • A viable approach for ‘low-risk’ patients labelled with penicillin allergy? (link)

  • No Clinical Benefit to Treating Male Urinary Tract Infection Longer than Seven Days: An Outpatient Database Study (link)

  • The Role of Ertapenem for the Treatment of Complicated Intra-abdominal Infections With a Positive Culture for Enterococcus faecalis (link)

  • Cefazolin Versus Anti-Staphylococcal Penicillins for the Treatment of Patients with Methicillin-Susceptible Staphylococcus aureus Infection: A Meta-Analysis with Trial Sequential Analysis (link)

  • Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion (link)

  • A Systematic Review of Single-Dose Aminoglycoside Therapy for Urinary Tract Infection: Is It Time To Resurrect an Old Strategy? (link)

  • Utility of prior cultures in predicting antibiotic resistance of bloodstream infections due to Gram-negative pathogens: a multicentre observational cohort study (link)

  • Catheter-related bloodstream infections with coagulase-negative Staphylococci: are antibiotics necessary if the catheter is removed? (link)

  • You can't always get what you want, but if you try sometimes (with two tests—TST and IGRA—for tuberculosis) you get what you need (link)

  • Fluoroquinolone-based versus beta lactam-based regimens for complicated intra-abdominal infections: a meta-analysis of randomized controlled trials (link)

  • The dosing and monitoring of vancomycin: what is the best way forward? (link)

  • Antibiotic allergy (Lancet)(link)

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