Previous Highlights

November 2019

Oral vs Intravenous Antibiotics for Patients With Klebsiella pneumoniae Liver Abscess: A Randomized, Controlled Noninferiority Study

Link to the summary is HERE.

October 2019

Antibiotic treatment for 6 days versus 12 days in patients with severe cellulitis: a multicentre randomised, double-blind, placebo-controlled, non-inferiority trial

Link to the summary is HERE.

 

Pneumococcal urinary antigen testing in US hospitals: A missed opportunity for antimicrobial stewardship

Link to the summary is HERE.

 

September 2019

Efficacy of ceftazidime-avobactam in monotherapy of combination therapy against CR GNB- a meta-analysis

Link to the summary is HERE.

Four versus six weeks of antibiotic therapy for osteoarticular infections after implant removal: a randomized trial

Link to the summary is HERE.

 

August 2019

Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients

Link to the summary is HERE.

 

Oral Fluoroquinolone or Trimethoprim-sulfamethoxazole vs. ß-lactams as Step-Down Therapy for Enterobacteriaceae Bacteremia: Systematic Review and Meta-analysis

Link to the the summary is HERE.

Effectiveness of a Bundled Intervention Including Adjunctive Corticosteroids on Outcomes of Hospitalized Patients with Community-Acquired Pneumonia: A Stepped-Wedge Randomized Clinical Trial

Link to the summary is HERE.

 

July 2019

Carbapenem-resistant Acinetobacter baumannii (CRAB): in pursuit of an effective treatment

Link to the summary is HERE.

When not to start antibiotics: avoiding antibiotic overuse in the

intensive care unit

Link to the summary is HERE.

Utility of Ophthalmologic Screening for Patients With Candida Bloodstream Infections- A Systematic Review

Link to the summary is HERE.

June 2019

Efficacy of Ceftriaxone 1 g daily Versus 2 g daily for The Treatment of Community-Acquired Pneumonia: A Systematic Review with Meta-Analysis

Link to the summary is HERE.

Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial

Link to the summary is HERE.

Direct Oral Amoxicillin Challenge: A viable approach for "low-risk" patients labelled with penicillin allergy (PenA)?

Link to the summary is HERE.

 

May 2019

Adverse Outcomes Associated with Potentially Inappropriate Antibiotic Use in Heart Failure Admissions

Link to the summary is HERE.

No Clinical Benefit to Treating Male Urinary Tract Infection Longer than Seven Days: An Outpatient Database Study

Link to the summary is HERE.

MERINO Trial: Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients with E.coli or Klebsiella pneumoniae Bloodstream Infection & Ceftriaxone Resistance

Link to the summary is HERE.

The Role of Ertapenem for the Treatment of Complicated Intra-abdominal Infections With a Positive Culture for Enterococcus faecalis

Link to the summary is HERE.

 

April 2019

Association of Duration and Type of Surgical Prophylaxis With Antimicrobial-Associated Adverse Events

Link to the summary is HERE.

 

Defining the Breakpoint Duration of Staphylococcus aureus Bacteremia Predictive of Poor Outcomes​

Link to the summary is HERE.

Duration of Exposure to Antipseudomonal beta-Lactam Antibiotics in the Critically Ill and Development of New Resistance
Link to the summary is HERE.

March 2019

Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteremia: a systematic review and meta-analysis

Link to the summary is HERE.

 

Antibiotic therapy for Pseudomonas aeruginosa blood stream infections;

HOW LONG IS ENOUGH?

Link to the summary is HERE.

Clinical Data on Daptomycin Plus Ceftaroline Versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia

Link to the summary is HERE.

A Systematic Review of Single-Dose Aminoglycoside Therapy for Urinary Tract Infection: Is It Time To Resurrect an Old Strategy

Link to the summary is HERE.

Antibiotic treatment duration for bacteremia due to Enterobacteriaceae: A systematic review and meta-analysis

Link to the summary is HERE.

Feb 2019

Utility of prior cultures in predicting antibiotic resistance of bloodstream infections due to Gram-negative pathogens: a multi centre observational cohort study

Link to the summary is HERE.

Catheter related BSI with coagulase negative Staph. Are antibiotics necessary if the catheter is removed

Link to the summary is HERE.

JAN 2019

 You can't always get what you want, but if you try sometimes (with two tests—TST and IGRA—for tuberculosis) you get what you need

Link to the summary is HERE.

Fluoroquinolone-based vs. beta lactam-based regimens for complicated intra-abdominal infections: a meta-analysis of randomized controlled trials

Link to the summary is HERE.

The dosing and monitoring of vancomycin –

what is the best way forward? 

Link to the summary is HERE.

DEC 2018

Antibiotic Allergy - Lancet 2018.

Link to the summary is HERE.

SEPTEMBER 2018

Can we do IV Oral switch in Endocarditis Treatment?

Link to the summary is HERE.

 

AUGUST 2018

Stewardship in vancomycin (VANC) - Are we doing it right when come to therapeutic drug monitoring (TDM)?

Link to the summary is HERE.

How to "prophylax" cancer patients against invasive aspergillosis (IA) using anti-fungal agents?

Link to the summary is HERE.

 

JULY 2018

Driving sustainable change in antimicrobial prescribing practice: how can social and behavioral sciences help?

Link to the summary is HERE.

 

What happens if you add NO MRSA and Pseudomonas in the respi culture report for clinicians

Link to the summary is HERE

 

Do we need colistin empirically in CRE and carbapenem resistant Acinetobacter infections?

Link to the summary is HERE.

MAY 2018

'Careful goodbye at the door': is there a role for antimicrobial stewardship interventions for antimicrobial therapy prescribed on hospital discharge?

Link to the summary is HERE

 

APRIL 2018

Antibiotic stewardship in low- and middle-income countries (LMICs): the same but different?

Link to the summary is HERE